Integrated Prostate Cytomolecular Testing Overview
A concise physician-facing overview of the service, report structure, and clinical value.
Open PDF →A prostate-focused diagnostic service that brings prostate FNA cytology, TMPRSS2-ERG FISH, whole-gland sector mapping, and a Genetic Complexity Score (GCS) together into a single structured report. The approach is designed to provide a broader, sector-based perspective across the gland — and to complement MRI, core needle biopsy, and other clinical information.
IPCT combines morphologic, molecular, spatial, and biologic information into a single structured interpretation. Together, the four components are designed to support a broader, sector-based read of the gland rather than a view limited to a single sampled focus.
Fine-needle aspiration provides cellular, morphologic assessment of sampled tissue. Cytologic review supports characterization of each sector and forms the morphologic foundation of the integrated interpretation.
Fluorescence in situ hybridization for the TMPRSS2-ERG rearrangement adds complementary molecular information to morphologic review, contributing biologic context that cytology alone does not provide.
Multi-sector sampling across the prostate supports a spatial, whole-gland perspective rather than a view centered on a single tumor focus. Sectors may be reported as concordant, discordant, indeterminate, or negative, and may help characterize focality and laterality across the gland.
Morphologic, molecular, and spatial findings are reviewed together and delivered as a structured synoptic report that includes a Genetic Complexity Score (GCS) to add biologic context and support multidisciplinary communication.
The integrated format is designed to complement MRI, histopathology, core needle biopsy, and other clinical data. It does not replace them. Its value is in how morphologic, molecular, and spatial information are organized together to support a broader, sector-based view of the gland during diagnostic and treatment conversations.
Sector-level results are structured so they can be read alongside MRI, PSA trends, and prior histopathology, supporting correlation across imaging and tissue-based information.
Whole-gland sampling may identify findings outside the dominant lesion, including concordant, discordant, indeterminate, and negative sectors that can inform how the case is interpreted as a whole.
Structured, sector-based reporting may assist biopsy planning, treatment planning, focality and laterality assessment, and multidisciplinary interpretation by making the spatial distribution of findings easier to reference across the care team.
IPCT is intended to complement core needle biopsy and other prostate cancer tests, contributing integrated morphologic, molecular, and spatial information to multidisciplinary review rather than substituting for existing workflows.
Download physician-facing reference material related to Integrated Prostate Cytomolecular Testing.
A concise physician-facing overview of the service, report structure, and clinical value.
Open PDF →A physician-facing case companion followed by a sample Integrated Prostate Cytomolecular Report.
Open PDF →We work with urology practices and clinical teams involved in prostate cancer diagnosis and treatment. Share a little about your setting and a member of our team will follow up to discuss how IPCT may fit into your workflow.